Different grades of diabetic retinopathy correlate with tear and ocular surface function in diabetic patients without subjective symptoms of dry eye.

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This is an interesting article in that it documents that diabetic patients have morphological surface cell changes as measured by impression cytology. Patients were qualified as not having dry eye on the basis of a McMonnies symptom questionnaire. Given that over 50% of diabetic patients have reduced corneal sensation, it is likely … [Read more...]

Effect of tear hyperosmolarity and signs of clinical ocular surface pathology upon conjunctival goblet cell function in the human ocular surface.

Tear Osmolarity continues to be investigated internationally with the TearLab device.  This abstract from IOVS.ORG discusses tear osmolarity and it s relationship to ocular surface disease and goblet cell function. IOVS.ORG Investigative Ophthalmology & Visual … [Read more...]

sPLA2-IIa Amplifies Ocular Surface Inflammation in the Experimental Dry Eye

More and more research is focusing on the biomarkers found in tears as this interesting abstract discusses sPLA@-IIa which is a biomarker for inflammatory diseases in humans and is found in high levels in tears.  IOVS is publishing what we have seen to be the first report of its involvement in ocular surface inflammation and also … [Read more...]

Screening for Dry Eye With Newly Developed Ocular Surface Thermographer

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From American Journal of Ophthalmology an interesting  abstract discusses an Ocular Surface Thermographer being used for Dry Eye Disease Screener showing a decrease in ocular surface temperature in dry eye patients compared to … [Read more...]