Clinical Utility of Objective Tests for Dry Eye Disease: Variability Over Time and Implications for Clinical Trials and Disease Management.

tearlab test for dry eye disease

In a recent pre-publication release in the "Cornea" journal, tear osmolarity showed both treatment response and evidence of lower variability compared with other commonly used signs of Dry Eye Disease (DED).  The study included DED patients being treated over a 3 month period utilizing topical cyclosporine 0.05% (Restasis).  By … [Read more...]

Symptom-based approaches do not seem appropriate for MGD estimation

Asymptomatic MGD is more common than Symptomatic according to an article soon to be published in IOVS.  In fact asymptomatic patients were more than two times more prevalent than those with symptoms. This publication is significant as it demonstrates if clinicians rely only symptoms of meibomian gland disfunction before evaluating … [Read more...]

Effects of Obstructive Sleep Apnea Syndrome on the Ocular Surface

More and more patients are being treated for obstructive sleep apnea as evidence builds showing the harmful effects of this condition involving Glaucoma and Dry Eye Disease.  Cornea 2012 Mar. 9 (Epub head of print) article by Hayirici, et al discusses its potential effect of CPAP on the ocular surface.  Patients may benefit from … [Read more...]

Dry Eye Disease & Depression. Is it the Chicken or the Egg?

We see patients every day that are being treated with antidepressants, suffering from depression to OCD to anxiety.  Clinicians should be aware Dry Eye Disease has significant impact on these patients' quality of life. Published in Cornea Feb 2012(Epub ahead of print)  at this … [Read more...]

A Single LipiFlow® Thermal Pulsation System Treatment Improves Meibomian Gland Function and Reduces Dry Eye Symptoms for 9 Months

Promising results regarding treatment for MGD patients using LipiFlow device reduced DED symptoms. To view the article, click here: http://informahealthcare.com/doi/abs/10.3109/02713683.2011.631721 … [Read more...]

Using TearLab for Dry Eye Detection in Refractive Surgery Patients

In a poster presented at the winter ESCRS, the TearLab Osmolarity Test and Schirmer's test were compared to see which is a more accurate predictor of post-refractive surgery dry eye disease when performed in pre-operative refractive surgery patients. Results showed that by the end of postoperative month 1, pre-LASIK … [Read more...]

Insights Into The Role of Osmolarity

Stephen Pflugfelder, MD provided a number of dry eye pearls in his article, “Tear Dysfunction and the Cornea: LXVIII Edward Jackson Memorial Lecture” published inthe December 2011 issue of American Journal of Ophthalmology. http://www.ncbi.nlm.nih.gov/pubmed/22019306 Regarding osmolarity and its role in dry eye, Dr. … [Read more...]

Its just Dry Eye Disease, or is it?

How many times have we as clinicians initially presumed "a default diagnosis" of Dry Eye Disease just based on symptoms?  Dr. Bill Townsend discusses Conjunctivochalasis which is an example of "other causes" we must remember when patients are having symptoms of Dry Eye Disease. Conjunctivochalasis By William Townsend, OD, … [Read more...]

Chronic BAK exposure is associated with an increase in tear osmolarity

Dr. Eldridge began an interesting thread this past week regarding ocular surface disease in glaucoma patients. He reminded us that dry eye disease can often be silent in patients after chronic administration of BAK preservatives have reduced corneal … [Read more...]

Chronic administration of BAK appears to alter corneal sensitivity

Ocular Surface Disease can be a major problem for glaucoma patients and could result in cell damage, discomfort, loss of quality of vision as well as Quality of Life issues.  Patients may not be able to give reliable feedback regarding dry eye disease.  In the Dec 2011 Journal of French Ophthalmology, Van Went et al evaluated … [Read more...]