We have known for years BAK is often a cause for ocular discomfort for patients. "Effects of preservative-free tafluprost on tear film osmolarity, tolerability, and intraocular pressure in previously treated patients with open-angle glaucoma" in Clinical Ophthalmology Jan 2012 looks at tear osmolarity, corneal staining and OSDI in … [Read more...]
Recent study shows preservative-free tafluprost offers effective treatment with less ocular surface impact for glaucoma patients
January 18, 2012 By Leave a Comment
Diurnal variation of tear osmolarity in normal subjects measured by a new microchip system
January 11, 2012 By Leave a Comment
Normal subjects showed no variation over a day, confirming that a properly functioning tear film is characterized by its low and stable concentration. This study provides further evidence that eye-to-eye variability is the hallmark of Dry Eye Disease. As shown in Lemp et al. [AJO 2011], dry eye disease subjects showed … [Read more...]
Link Between Ocular Surface Disease and Quality of Life in Glaucoma Patients
January 10, 2012 By Leave a Comment
A link between Quality of Life scores in patients treated for Dry Eye Disease and Glaucoma is documented in the Jan. 2012 American Journal of Ophthalmology publication. As clinicians we need to be aware of the decrease in QOL with increasing Glaucoma severity by monitoring the ocular surface carefully. Link Between Ocular … [Read more...]
Depression and Dry Eye in the Elderly
November 3, 2011 By Leave a Comment
Depression is not uncommon in the average practice and this study shows further evidence of Dry Eye Disease's significant impact on depression. Depression and Dry Eye in the Elderly Korean investigators conducted a population-based cross-sectional study to examine the association between depression and dry eye disease (DED) … [Read more...]
The Effect of Oral Supplementation of Omega-3 and Omega-6 Fatty Acids on a Conjunctival Inflammatory Marker in Dry Eye Patients
September 14, 2011 By Leave a Comment
Omega 3 & 6 continue to be a major focus in Dry Eye Disease research and this abstract shows a reduction in inflammatory marker HLA-DR in patients using impression cytology. The Effect of Oral Supplementation of Omega-3 and Omega-6 Fatty Acids on a Conjunctival Inflammatory Marker in Dry Eye Patients. This 3-month, … [Read more...]
Dry Eye Syndrome Associated With Several Risk Factors in US Veterans
September 8, 2011 By Leave a Comment
Clinicians need to be aware that US veterans may suffer from Dry Eye along with post-traumatic stress disorder. Common medications such as antidepressants and antianxiety drugs may cause &/or exacerbate these patients' condition. See the summary from the online ahead of print AJO article soon to be out... Dry Eye … [Read more...]
Dry Eye Syndrome To Become Most Common Eye Disease in Baby Boomers
June 7, 2011 By Leave a Comment
Dry eye expert Dr. David Kisling reports that Dry Eye Syndrome will be the most prevalent eye disorder the Baby Boomer generation faces in the future. Shifting demographics in an aging population will result in a tidal wave of dry eye problems by 2030. Read on to discover why this epidemic growth of dry eye disease is threatening … [Read more...]
Different grades of diabetic retinopathy correlate with tear and ocular surface function in diabetic patients without subjective symptoms of dry eye.
May 24, 2011 By Leave a Comment
This is an interesting article in that it documents that diabetic patients have morphological surface cell changes as measured by impression cytology. Patients were qualified as not having dry eye on the basis of a McMonnies symptom questionnaire. Given that over 50% of diabetic patients have reduced corneal sensation, it is likely … [Read more...]
Effect of tear hyperosmolarity and signs of clinical ocular surface pathology upon conjunctival goblet cell function in the human ocular surface.
May 18, 2011 By Leave a Comment
Tear Osmolarity continues to be investigated internationally with the TearLab device. This abstract from IOVS.ORG discusses tear osmolarity and it s relationship to ocular surface disease and goblet cell function. IOVS.ORG Investigative Ophthalmology & Visual … [Read more...]
sPLA2-IIa Amplifies Ocular Surface Inflammation in the Experimental Dry Eye
May 5, 2011 By Leave a Comment
More and more research is focusing on the biomarkers found in tears as this interesting abstract discusses sPLA@-IIa which is a biomarker for inflammatory diseases in humans and is found in high levels in tears. IOVS is publishing what we have seen to be the first report of its involvement in ocular surface inflammation and also … [Read more...]
